Drug interactions
Brexpiprazole + Chlordiazepoxide-clidinium
Severity: Moderate
Brexpiprazole and Chlordiazepoxide-clidinium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause sedation, so combined use may increase drowsiness and impair psychomotor function. Orthostatic dizziness may also be more likely.
What this interaction means in plain words
Brexpiprazole and Chlordiazepoxide-clidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brexpiprazole belongs to Central Nervous System; Chlordiazepoxide-clidinium belongs to Gastrointestinal Tract.
Why it happens
Additive CNS depression.
What to do
Monitor for sedation and dizziness, especially after dose changes. Counsel on driving and machinery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chlordiazepoxide-clidinium
- Alfentanil + Chlordiazepoxide-clidinium Major
- Alprazolam + Chlordiazepoxide-clidinium Major
- Amobarbital + Chlordiazepoxide-clidinium Major
- Belladonna and opium + Chlordiazepoxide-clidinium Major
- Benzhydrocodone / acetaminophen + Chlordiazepoxide-clidinium Major
- Brexanolone + Chlordiazepoxide-clidinium Major
Other interactions of Brexpiprazole
Frequently asked questions
Can I take Brexpiprazole with Chlordiazepoxide-clidinium?
MediHelp rates the interaction as moderate. Brexpiprazole and Chlordiazepoxide-clidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause sedation, so combined use may increase drowsiness and impair psychomotor function. Orthostatic dizziness may also be more likely.
How serious is the interaction between Brexpiprazole and Chlordiazepoxide-clidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation and dizziness, especially after dose changes. Counsel on driving and machinery.
What other medicines interact with Chlordiazepoxide-clidinium?
MediHelp also lists interactions of Chlordiazepoxide-clidinium with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide-clidinium page.
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