Drug interactions
Brimonidine + Sotalol
Severity: Minor
Brimonidine and Sotalol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brimonidine is an ophthalmic alpha-2 agonist with modest systemic absorption that can lower heart rate and blood pressure. Additive hypotension or bradycardia with sotalol is possible but generally small.
What this interaction means in plain words
Brimonidine and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brimonidine belongs to Miscellaneous; Sotalol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic reduction of heart rate and blood pressure via central sympatholytic effect.
What to do
Monitor heart rate and blood pressure in patients with bradycardia or hypotension. No routine adjustment is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sotalol
- Arsenic trioxide + Sotalol Contraindicated
- Artemether / lumefantrine + Sotalol Contraindicated
- Disopyramide + Sotalol Contraindicated
- Dofetilide + Sotalol Contraindicated
- Dronedarone + Sotalol Contraindicated
- Droperidol + Sotalol Contraindicated
Other interactions of Brimonidine
- Brimonidine + Isocarboxazid Contraindicated
- Brimonidine + Linezolid Contraindicated
- Brimonidine + Phenelzine Contraindicated
- Brimonidine + Procarbazine Contraindicated
- Brimonidine + Rasagiline Contraindicated
- Brimonidine + Selegiline Contraindicated
Frequently asked questions
Can I take Brimonidine with Sotalol?
MediHelp rates the interaction as minor. Brimonidine and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brimonidine is an ophthalmic alpha-2 agonist with modest systemic absorption that can lower heart rate and blood pressure. Additive hypotension or bradycardia with sotalol is possible but generally small.
How serious is the interaction between Brimonidine and Sotalol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure in patients with bradycardia or hypotension. No routine adjustment is needed.
What other medicines interact with Sotalol?
MediHelp also lists interactions of Sotalol with, for example, Arsenic trioxide, Artemether / lumefantrine, Disopyramide. The full list is on the Sotalol page.
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