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Drug interactions

Brivaracetam + Propofol

Severity: Minor

Brivaracetam and Propofol: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Brivaracetam can cause somnolence and dizziness, which may add to propofol sedation. The effect is usually modest.

What this interaction means in plain words

Brivaracetam and Propofol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Brivaracetam belongs to Central Nervous System; Propofol belongs to Central Nervous System.

Evidence level: Low

Why it happens

Additive central nervous system depression.

What to do

Titrate propofol to effect and monitor level of sedation in patients on brivaracetam.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Brivaracetam with Propofol?

MediHelp rates the interaction as minor. Brivaracetam and Propofol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brivaracetam can cause somnolence and dizziness, which may add to propofol sedation. The effect is usually modest.

How serious is the interaction between Brivaracetam and Propofol?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate propofol to effect and monitor level of sedation in patients on brivaracetam.

What other medicines interact with Propofol?

MediHelp also lists interactions of Propofol with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Propofol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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