Drug interactions
Brodalumab + Pneumococcal vaccine 13-valent
Severity: Minor
Brodalumab and Pneumococcal vaccine 13-valent: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brodalumab blocks IL-17 receptor signaling and may modestly affect immune function. Data on vaccine response during brodalumab are lacking, but an inactivated conjugate vaccine poses no infection risk and is not contraindicated.
What this interaction means in plain words
Brodalumab and Pneumococcal vaccine 13-valent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brodalumab belongs to Miscellaneous; Pneumococcal vaccine 13-valent belongs to Miscellaneous.
Why it happens
IL-17 receptor antagonism could theoretically alter vaccine immune response; no established effect.
What to do
Complete age-appropriate immunizations before starting brodalumab when feasible. Inactivated vaccines may still be given during therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Pneumococcal vaccine 13-valent
- Adalimumab + Pneumococcal vaccine 13-valent Moderate
- Alefacept + Pneumococcal vaccine 13-valent Moderate
- Anakinra + Pneumococcal vaccine 13-valent Moderate
- Anti-thymocyte + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin equine + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin rabbit + Pneumococcal vaccine 13-valent Moderate
Other interactions of Brodalumab
- Brodalumab + Upadacitinib Major
- Brodalumab + Warfarin Moderate
- Brodalumab + Carbamazepine Minor
- Brodalumab + Clonidine Minor
- Brodalumab + Cyclosporin Minor
- Brodalumab + Phenytoin Minor
Frequently asked questions
Can I take Brodalumab with Pneumococcal vaccine 13-valent?
MediHelp rates the interaction as minor. Brodalumab and Pneumococcal vaccine 13-valent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brodalumab blocks IL-17 receptor signaling and may modestly affect immune function. Data on vaccine response during brodalumab are lacking, but an inactivated conjugate vaccine poses no infection risk and is not contraindicated.
How serious is the interaction between Brodalumab and Pneumococcal vaccine 13-valent?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete age-appropriate immunizations before starting brodalumab when feasible. Inactivated vaccines may still be given during therapy if needed.
What other medicines interact with Pneumococcal vaccine 13-valent?
MediHelp also lists interactions of Pneumococcal vaccine 13-valent with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Pneumococcal vaccine 13-valent page.
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