Drug interactions
Brompheniramine + Cinnarizine
Severity: Moderate
Brompheniramine and Cinnarizine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have antihistaminic and sedative properties, so combining them increases drowsiness and psychomotor impairment. Cinnarizine can also cause anticholinergic effects and, rarely, extrapyramidal symptoms.
What this interaction means in plain words
Brompheniramine and Cinnarizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brompheniramine belongs to Respiratory; Cinnarizine belongs to Respiratory.
Why it happens
Additive central H1-receptor blockade and sedation.
What to do
Avoid the combination where possible and advise against driving or operating machinery. Reduce the dose or stop one agent if excessive sedation occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brompheniramine
Other interactions of Cinnarizine
- Alprazolam + Cinnarizine Moderate
- Amitriptyline + Cinnarizine Moderate
- Amobarbital + Cinnarizine Moderate
- Aripiprazole + Cinnarizine Moderate
- Azelastine-fluticasone + Cinnarizine Moderate
- Azelastine + Cinnarizine Moderate
Frequently asked questions
Can I take Brompheniramine with Cinnarizine?
MediHelp rates the interaction as moderate. Brompheniramine and Cinnarizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have antihistaminic and sedative properties, so combining them increases drowsiness and psychomotor impairment. Cinnarizine can also cause anticholinergic effects and, rarely, extrapyramidal symptoms.
How serious is the interaction between Brompheniramine and Cinnarizine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible and advise against driving or operating machinery. Reduce the dose or stop one agent if excessive sedation occurs.
What other medicines interact with Brompheniramine?
MediHelp also lists interactions of Brompheniramine with, for example, Alfentanil, Belladonna and opium, Benzhydrocodone / acetaminophen. The full list is on the Brompheniramine page.
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