Drug interactions
Brompheniramine + Flibanserin
Severity: Moderate
Brompheniramine and Flibanserin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine is a sedating antihistamine, and combined use with flibanserin can increase drowsiness and reduce alertness. The effect is mostly additive and dose related.
What this interaction means in plain words
Brompheniramine and Flibanserin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brompheniramine belongs to Respiratory; Flibanserin belongs to Genitourinary.
Why it happens
Additive pharmacodynamic CNS depression.
What to do
Advise patients about drowsiness and prefer a non-sedating antihistamine if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Flibanserin?
MediHelp rates the interaction as moderate. Brompheniramine and Flibanserin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Brompheniramine is a sedating antihistamine, and combined use with flibanserin can increase drowsiness and reduce alertness. The effect is mostly additive and dose related.
How serious is the interaction between Brompheniramine and Flibanserin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients about drowsiness and prefer a non-sedating antihistamine if needed.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
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