Drug interactions
Brompheniramine + Haloperidol
Severity: Moderate
Brompheniramine and Haloperidol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine is a sedating first-generation antihistamine with anticholinergic properties. Together with haloperidol it can increase drowsiness, psychomotor impairment and anticholinergic effects.
What this interaction means in plain words
Brompheniramine and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brompheniramine belongs to Respiratory; Haloperidol belongs to Central Nervous System.
Why it happens
Additive CNS depression and antimuscarinic effects.
What to do
Counsel on sedation and avoid driving or alcohol. Prefer a non-sedating antihistamine in elderly patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Haloperidol?
MediHelp rates the interaction as moderate. Brompheniramine and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Brompheniramine is a sedating first-generation antihistamine with anticholinergic properties. Together with haloperidol it can increase drowsiness, psychomotor impairment and anticholinergic effects.
How serious is the interaction between Brompheniramine and Haloperidol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on sedation and avoid driving or alcohol. Prefer a non-sedating antihistamine in elderly patients.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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