Drug interactions
Brompheniramine + Lasmiditan
Severity: Moderate
Brompheniramine and Lasmiditan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan commonly causes dizziness and sedation, and brompheniramine may add to these effects. The combination has not been formally studied.
What this interaction means in plain words
Brompheniramine and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brompheniramine belongs to Respiratory; Lasmiditan belongs to Central Nervous System.
Why it happens
Additive CNS depression from 5-HT1F agonism and H1 antagonism.
What to do
Counsel patients to avoid driving for at least 8 hours after each lasmiditan dose. Avoid additional sedatives if possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brompheniramine
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Brompheniramine with Lasmiditan?
MediHelp rates the interaction as moderate. Brompheniramine and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan commonly causes dizziness and sedation, and brompheniramine may add to these effects. The combination has not been formally studied.
How serious is the interaction between Brompheniramine and Lasmiditan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid driving for at least 8 hours after each lasmiditan dose. Avoid additional sedatives if possible.
What other medicines interact with Brompheniramine?
MediHelp also lists interactions of Brompheniramine with, for example, Alfentanil, Belladonna and opium, Benzhydrocodone / acetaminophen. The full list is on the Brompheniramine page.
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