Drug interactions
Brompheniramine + Nabilone
Severity: Moderate
Brompheniramine and Nabilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine is a sedating first-generation antihistamine, and nabilone also causes drowsiness. Their combination may deepen sedation and impair concentration and psychomotor performance, and anticholinergic effects may add to nabilone's tachycardia and dizziness.
What this interaction means in plain words
Brompheniramine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brompheniramine belongs to Respiratory; Nabilone belongs to Gastrointestinal Tract.
Why it happens
Additive central nervous system depression through pharmacodynamic synergy.
What to do
Monitor for excessive drowsiness and consider a non-sedating antihistamine. Advise against driving or operating machinery until the response is known.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabilone
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Nabilone?
MediHelp rates the interaction as moderate. Brompheniramine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Brompheniramine is a sedating first-generation antihistamine, and nabilone also causes drowsiness. Their combination may deepen sedation and impair concentration and psychomotor performance, and anticholinergic effects may add to nabilone's tachycardia and dizziness.
How serious is the interaction between Brompheniramine and Nabilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive drowsiness and consider a non-sedating antihistamine. Advise against driving or operating machinery until the response is known.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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