Drug interactions
Budesonide + Elagolix
Severity: Minor
Budesonide and Elagolix: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix is a weak-to-moderate CYP3A4 inducer and may lower budesonide exposure, while it also inhibits P-glycoprotein, which may raise it. The net effect is uncertain and probably small.
What this interaction means in plain words
Budesonide and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Elagolix belongs to Musculoskeletal.
Why it happens
Opposing effects of CYP3A4 induction and P-glycoprotein inhibition by elagolix on budesonide disposition.
What to do
Monitor for changes in budesonide efficacy or adverse effects and adjust dose only if clinically indicated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Budesonide with Elagolix?
MediHelp rates the interaction as minor. Budesonide and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak-to-moderate CYP3A4 inducer and may lower budesonide exposure, while it also inhibits P-glycoprotein, which may raise it. The net effect is uncertain and probably small.
How serious is the interaction between Budesonide and Elagolix?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for changes in budesonide efficacy or adverse effects and adjust dose only if clinically indicated.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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