Drug interactions
Budesonide + Human papillomavirus vaccine
Severity: Minor
Budesonide and Human papillomavirus vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled or locally acting budesonide has little systemic immunosuppression and is unlikely to affect HPV vaccine response. Only higher systemic exposure might modestly reduce the response.
What this interaction means in plain words
Budesonide and Human papillomavirus vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Human papillomavirus vaccine belongs to Miscellaneous.
Why it happens
Systemic glucocorticoid effects on lymphocytes could reduce immunogenicity, but exposure to budesonide is low because of high first-pass metabolism.
What to do
No change is needed; vaccinate as scheduled.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Moderate
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Moderate
- Atidarsagene autotemcel + Human papillomavirus vaccine Moderate
- Belimumab + Human papillomavirus vaccine Moderate
- Cortisone + Human papillomavirus vaccine Moderate
- Cyclosporine + Human papillomavirus vaccine Moderate
Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Human papillomavirus vaccine?
MediHelp rates the interaction as minor. Budesonide and Human papillomavirus vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inhaled or locally acting budesonide has little systemic immunosuppression and is unlikely to affect HPV vaccine response. Only higher systemic exposure might modestly reduce the response.
How serious is the interaction between Budesonide and Human papillomavirus vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is needed; vaccinate as scheduled.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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