Drug interactions
Budesonide-formoterol + Ephedrine
Severity: Moderate
Budesonide-formoterol and Ephedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ephedrine is a sympathomimetic and formoterol is a beta-2 agonist, so combined use can intensify cardiovascular stimulation. Patients may experience palpitations, raised blood pressure, tachyarrhythmias, tremor and a fall in serum potassium.
What this interaction means in plain words
Budesonide-formoterol and Ephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Ephedrine belongs to Cardiovascular.
Why it happens
Additive adrenergic stimulation, with beta-2 mediated intracellular potassium shift.
What to do
Monitor blood pressure, pulse and symptoms of arrhythmia, and check potassium in patients at risk. Avoid in patients with significant cardiovascular disease where possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Ephedrine
- Ephedrine + Isocarboxazid Contraindicated
- Ephedrine + Phenelzine Contraindicated
- Ephedrine + Procarbazine Contraindicated
- Ephedrine + Rasagiline Contraindicated
- Ephedrine + Selegiline Contraindicated
- Ephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Ephedrine?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Ephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ephedrine is a sympathomimetic and formoterol is a beta-2 agonist, so combined use can intensify cardiovascular stimulation. Patients may experience palpitations, raised blood pressure, tachyarrhythmias, tremor and a fall in serum potassium.
How serious is the interaction between Budesonide-formoterol and Ephedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, pulse and symptoms of arrhythmia, and check potassium in patients at risk. Avoid in patients with significant cardiovascular disease where possible.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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