Drug interactions
Budesonide-formoterol + Esmolol
Severity: Moderate
Budesonide-formoterol and Esmolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Esmolol blocks beta-receptors and can oppose the bronchodilating effect of formoterol. Although esmolol is cardioselective and short-acting, it may still provoke bronchospasm in patients with asthma or COPD who rely on formoterol.
What this interaction means in plain words
Budesonide-formoterol and Esmolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Esmolol belongs to Cardiovascular.
Why it happens
Pharmacodynamic antagonism at beta-adrenergic receptors.
What to do
Use esmolol only when clearly needed in patients with reactive airway disease and monitor respiratory status closely. Have a rescue bronchodilator available and stop esmolol if bronchospasm develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Esmolol
- Acebutolol + Esmolol Major
- Amifostine + Esmolol Major
- Amiodarone + Esmolol Major
- Celiprolol + Esmolol Major
- Diltiazem + Esmolol Major
- Epinephrine racemic + Esmolol Major
Frequently asked questions
Can I take Budesonide-formoterol with Esmolol?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Esmolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Esmolol blocks beta-receptors and can oppose the bronchodilating effect of formoterol. Although esmolol is cardioselective and short-acting, it may still provoke bronchospasm in patients with asthma or COPD who rely on formoterol.
How serious is the interaction between Budesonide-formoterol and Esmolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use esmolol only when clearly needed in patients with reactive airway disease and monitor respiratory status closely. Have a rescue bronchodilator available and stop esmolol if bronchospasm develops.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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