Drug interactions
Budesonide-formoterol + Gilteritinib
Severity: Moderate
Budesonide-formoterol and Gilteritinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gilteritinib is associated with QT prolongation and formoterol may also prolong the QT interval. Coadministration may increase the risk of ventricular arrhythmias including torsades de pointes.
What this interaction means in plain words
Budesonide-formoterol and Gilteritinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Gilteritinib belongs to Oncology.
Why it happens
Additive QT prolongation.
What to do
Monitor ECG and electrolytes, correcting potassium and magnesium abnormalities. Consider an alternative if QTc becomes markedly prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Gilteritinib
- Gilteritinib + Pimozide Contraindicated
- Amiodarone + Gilteritinib Major
- Amisulpride + Gilteritinib Major
- Amitriptyline + Gilteritinib Major
- Anagrelide + Gilteritinib Major
- Apalutamide + Gilteritinib Major
Frequently asked questions
Can I take Budesonide-formoterol with Gilteritinib?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Gilteritinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gilteritinib is associated with QT prolongation and formoterol may also prolong the QT interval. Coadministration may increase the risk of ventricular arrhythmias including torsades de pointes.
How serious is the interaction between Budesonide-formoterol and Gilteritinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes, correcting potassium and magnesium abnormalities. Consider an alternative if QTc becomes markedly prolonged.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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