Drug interactions
Budesonide-formoterol + Labetalol
Severity: Major
Budesonide-formoterol and Labetalol: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Labetalol blocks beta-receptors and can oppose formoterol's bronchodilation. In patients with asthma or COPD it may provoke bronchospasm and reduce response to formoterol.
What this interaction means in plain words
Budesonide-formoterol and Labetalol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Budesonide-formoterol belongs to Respiratory; Labetalol belongs to Cardiovascular.
Why it happens
Pharmacodynamic antagonism at beta-2 adrenergic receptors by non-selective beta blockade.
What to do
Avoid labetalol in patients with asthma and prefer a cardioselective agent or alternative class if an antihypertensive is needed. If unavoidable, monitor respiratory function closely.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Budesonide-formoterol
Other interactions of Labetalol
- Amifostine + Labetalol Major
- Amiodarone + Labetalol Major
- Atenolol-chlorthalidone + Labetalol Major
- Atenolol + Labetalol Major
- Betaxolol + Labetalol Major
- Bisoprolol + Labetalol Major
Frequently asked questions
Can I take Budesonide-formoterol with Labetalol?
MediHelp rates the interaction as major. Budesonide-formoterol and Labetalol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Labetalol blocks beta-receptors and can oppose formoterol's bronchodilation. In patients with asthma or COPD it may provoke bronchospasm and reduce response to formoterol.
How serious is the interaction between Budesonide-formoterol and Labetalol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid labetalol in patients with asthma and prefer a cardioselective agent or alternative class if an antihypertensive is needed. If unavoidable, monitor respiratory function closely.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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