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Drug interactions

Budesonide-formoterol + Macimorelin

Severity: Minor

Budesonide-formoterol and Macimorelin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Glucocorticoids can alter growth hormone secretion and might affect the accuracy of the macimorelin growth hormone stimulation test. Inhaled budesonide has low systemic exposure, so the effect is uncertain.

What this interaction means in plain words

Budesonide-formoterol and Macimorelin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Budesonide-formoterol belongs to Respiratory; Macimorelin belongs to Endocrine.

Evidence level: Low

Why it happens

Possible interference with pituitary growth hormone release; not firmly established for inhaled budesonide.

What to do

Interpret the macimorelin test with awareness of corticosteroid use, and follow labeling on washout of drugs affecting GH release where feasible.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Budesonide-formoterol with Macimorelin?

MediHelp rates the interaction as minor. Budesonide-formoterol and Macimorelin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucocorticoids can alter growth hormone secretion and might affect the accuracy of the macimorelin growth hormone stimulation test. Inhaled budesonide has low systemic exposure, so the effect is uncertain.

How serious is the interaction between Budesonide-formoterol and Macimorelin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Interpret the macimorelin test with awareness of corticosteroid use, and follow labeling on washout of drugs affecting GH release where feasible.

What other medicines interact with Budesonide-formoterol?

MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.

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