Drug interactions
Budesonide-formoterol + Moxifloxacin
Severity: Major
Budesonide-formoterol and Moxifloxacin: major interaction.
Last updated Sources: UK SmPC
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxifloxacin is a recognised QT-prolonging fluoroquinolone, and formoterol can add to this and lower potassium. The combination increases the risk of torsades de pointes.
What this interaction means in plain words
Budesonide-formoterol and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Budesonide-formoterol belongs to Respiratory; Moxifloxacin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia.
What to do
Choose a non-QT-prolonging antibiotic when feasible. If used together, check ECG and correct potassium and magnesium.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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References
Other interactions of Budesonide-formoterol
Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Moxifloxacin?
MediHelp rates the interaction as major. Budesonide-formoterol and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Moxifloxacin is a recognised QT-prolonging fluoroquinolone, and formoterol can add to this and lower potassium. The combination increases the risk of torsades de pointes.
How serious is the interaction between Budesonide-formoterol and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Choose a non-QT-prolonging antibiotic when feasible. If used together, check ECG and correct potassium and magnesium.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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