Drug interactions
Cabazitaxel + Oxaliplatin
Severity: Moderate
Cabazitaxel and Oxaliplatin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs cause myelosuppression, and combining them can deepen neutropenia and raise infection risk. Both also cause peripheral neuropathy.
What this interaction means in plain words
Cabazitaxel and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cabazitaxel belongs to Oncology; Oxaliplatin belongs to Oncology.
Why it happens
Additive myelosuppression and neurotoxicity from two cytotoxic agents.
What to do
Monitor blood counts and neuropathy, and consider growth factor support or dose reduction. When given sequentially, infuse the taxane before oxaliplatin.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cabazitaxel and Oxaliplatin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Other interactions of Cabazitaxel
Frequently asked questions
Can I take Cabazitaxel with Oxaliplatin?
MediHelp rates the interaction as moderate. Cabazitaxel and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs cause myelosuppression, and combining them can deepen neutropenia and raise infection risk. Both also cause peripheral neuropathy.
How serious is the interaction between Cabazitaxel and Oxaliplatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and neuropathy, and consider growth factor support or dose reduction. When given sequentially, infuse the taxane before oxaliplatin.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
