Drug interactions
Caffeine + Cinnarizine
Severity: Minor
Caffeine and Cinnarizine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Caffeine is a CNS stimulant that may partly counteract the drowsiness caused by cinnarizine. The effect is variable and rarely clinically important.
What this interaction means in plain words
Caffeine and Cinnarizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Caffeine belongs to Miscellaneous; Cinnarizine belongs to Respiratory.
Why it happens
Pharmacodynamic opposition between CNS stimulation and antihistamine sedation.
What to do
No action is needed. Do not rely on caffeine to offset sedation when driving or operating machinery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Caffeine
- Caffeine + Ephedrine Major
- Caffeine + Fezolinetant Major
- Caffeine + Methylenedioxymethamphetamine Major
- Caffeine + Selegiline transdermal Major
- Adenosine + Caffeine Moderate
- Benzphetamine + Caffeine Moderate
Other interactions of Cinnarizine
- Alprazolam + Cinnarizine Moderate
- Amitriptyline + Cinnarizine Moderate
- Amobarbital + Cinnarizine Moderate
- Aripiprazole + Cinnarizine Moderate
- Azelastine-fluticasone + Cinnarizine Moderate
- Azelastine + Cinnarizine Moderate
Frequently asked questions
Can I take Caffeine with Cinnarizine?
MediHelp rates the interaction as minor. Caffeine and Cinnarizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Caffeine is a CNS stimulant that may partly counteract the drowsiness caused by cinnarizine. The effect is variable and rarely clinically important.
How serious is the interaction between Caffeine and Cinnarizine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed. Do not rely on caffeine to offset sedation when driving or operating machinery.
What other medicines interact with Caffeine?
MediHelp also lists interactions of Caffeine with, for example, Ephedrine, Fezolinetant, Methylenedioxymethamphetamine. The full list is on the Caffeine page.
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