Drug interactions
Calcium acetate + Gemifloxacin
Severity: Moderate
Calcium acetate and Gemifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium acetate binds gemifloxacin in the gut and reduces its absorption, which can lower antibiotic levels and risk treatment failure.
What this interaction means in plain words
Calcium acetate and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium acetate belongs to Genitourinary; Gemifloxacin belongs to Anti Bacterial.
Why it happens
Chelation of gemifloxacin by calcium cations in the gastrointestinal tract.
What to do
Take gemifloxacin at least 2 hours before or 3 hours after calcium acetate. Check that the timing is kept if the calcium is a phosphate binder taken with meals.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Other interactions of Calcium acetate
Frequently asked questions
Can I take Calcium acetate with Gemifloxacin?
MediHelp rates the interaction as moderate. Calcium acetate and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium acetate binds gemifloxacin in the gut and reduces its absorption, which can lower antibiotic levels and risk treatment failure.
How serious is the interaction between Calcium acetate and Gemifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take gemifloxacin at least 2 hours before or 3 hours after calcium acetate. Check that the timing is kept if the calcium is a phosphate binder taken with meals.
What other medicines interact with Gemifloxacin?
MediHelp also lists interactions of Gemifloxacin with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Gemifloxacin page.
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