Drug interactions
Calcium + Cefdinir
Severity: Minor
Calcium and Cefdinir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium supplements may reduce cefdinir absorption, though the effect is modest and clearly documented for iron and some antacids. Reduced exposure could lower antibacterial effectiveness.
What this interaction means in plain words
Calcium and Cefdinir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium belongs to Gastrointestinal Tract; Cefdinir belongs to Anti Bacterial.
Why it happens
Possible chelation or reduced solubility in the gut; clear data are limited for calcium.
What to do
Give cefdinir at least 2 hours before or after calcium supplements.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Cefdinir
- Aluminum hydroxide + Cefdinir Moderate
- Cefdinir + Cholera vaccine Moderate
- Cefdinir + Famotidine Moderate
- Cefdinir + Gentamicin Moderate
- Cefdinir + Microbiota Moderate
- Cefdinir + Nizatidine Moderate
Frequently asked questions
Can I take Calcium with Cefdinir?
MediHelp rates the interaction as minor. Calcium and Cefdinir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium supplements may reduce cefdinir absorption, though the effect is modest and clearly documented for iron and some antacids. Reduced exposure could lower antibacterial effectiveness.
How serious is the interaction between Calcium and Cefdinir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give cefdinir at least 2 hours before or after calcium supplements.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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