Drug interactions
Calcium + Clevidipine
Severity: Moderate
Calcium and Clevidipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium given intravenously can counteract the vasodilating effect of calcium channel blockers such as clevidipine. Blood pressure control may be reduced. Oral calcium has little effect.
What this interaction means in plain words
Calcium and Clevidipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium belongs to Gastrointestinal Tract; Clevidipine belongs to Cardiovascular.
Why it happens
Pharmacodynamic antagonism, as raised extracellular calcium offsets calcium channel blockade.
What to do
Monitor blood pressure closely when intravenous calcium is given with clevidipine, and adjust the clevidipine infusion rate as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Clevidipine
Frequently asked questions
Can I take Calcium with Clevidipine?
MediHelp rates the interaction as moderate. Calcium and Clevidipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium given intravenously can counteract the vasodilating effect of calcium channel blockers such as clevidipine. Blood pressure control may be reduced. Oral calcium has little effect.
How serious is the interaction between Calcium and Clevidipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure closely when intravenous calcium is given with clevidipine, and adjust the clevidipine infusion rate as needed.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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