Drug interactions
Calcium carbonate + Chromium
Severity: Minor
Calcium carbonate and Chromium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium carbonate may reduce absorption of oral chromium supplements when taken together. The clinical effect is probably small.
What this interaction means in plain words
Calcium carbonate and Chromium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Chromium belongs to Gastrointestinal Tract.
Why it happens
Antacid-related rise in gastric pH and binding may reduce chromium absorption.
What to do
Separate administration by about 2 hours.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Other interactions of Chromium
- Chromium + Omadacycline Moderate
- Chromium + Sarecycline Moderate
- Acarbose + Chromium Minor
- Acetylsalicylic acid + Chromium Minor
- Alogliptin-metformin + Chromium Minor
- Alogliptin-pioglitazone + Chromium Minor
Frequently asked questions
Can I take Calcium carbonate with Chromium?
MediHelp rates the interaction as minor. Calcium carbonate and Chromium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium carbonate may reduce absorption of oral chromium supplements when taken together. The clinical effect is probably small.
How serious is the interaction between Calcium carbonate and Chromium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration by about 2 hours.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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