Drug interactions
Calcium carbonate + Felodipine
Severity: Minor
Calcium carbonate and Felodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium can in theory oppose the vasodilating action of calcium channel blockers. Clinically, oral calcium at usual doses rarely changes blood pressure control, though high intravenous calcium can.
What this interaction means in plain words
Calcium carbonate and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Felodipine belongs to Cardiovascular.
Why it happens
Pharmacodynamic antagonism of calcium channel blockade by raised extracellular calcium, which is significant mainly with parenteral calcium.
What to do
No routine change is needed with usual oral calcium supplementation; check blood pressure if high-dose calcium or hypercalcemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Calcium carbonate with Felodipine?
MediHelp rates the interaction as minor. Calcium carbonate and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium can in theory oppose the vasodilating action of calcium channel blockers. Clinically, oral calcium at usual doses rarely changes blood pressure control, though high intravenous calcium can.
How serious is the interaction between Calcium carbonate and Felodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed with usual oral calcium supplementation; check blood pressure if high-dose calcium or hypercalcemia occurs.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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