Drug interactions
Calcium chloride + Cholecalciferol
Severity: Moderate
Calcium chloride and Cholecalciferol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vitamin D increases calcium absorption, and with calcium chloride may contribute to hypercalcemia in susceptible patients. Calcium chloride is mainly given intravenously in acute settings, where the vitamin D effect is minor.
What this interaction means in plain words
Calcium chloride and Cholecalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Vitamin D enhances intestinal calcium absorption, adding to the calcium load.
What to do
Monitor serum calcium during combined use. Reduce the doses if hypercalcemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cholecalciferol
- Cholecalciferol + Digoxin Major
- Aluminum hydroxide + Cholecalciferol Moderate
- Calcium acetate + Cholecalciferol Moderate
- Calcium Carbonate + Cholecalciferol Moderate
- Calcium citrate + Cholecalciferol Moderate
- Calcium gluconate + Cholecalciferol Moderate
Frequently asked questions
Can I take Calcium chloride with Cholecalciferol?
MediHelp rates the interaction as moderate. Calcium chloride and Cholecalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vitamin D increases calcium absorption, and with calcium chloride may contribute to hypercalcemia in susceptible patients. Calcium chloride is mainly given intravenously in acute settings, where the vitamin D effect is minor.
How serious is the interaction between Calcium chloride and Cholecalciferol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium during combined use. Reduce the doses if hypercalcemia occurs.
What other medicines interact with Cholecalciferol?
MediHelp also lists interactions of Cholecalciferol with, for example, Digoxin, Aluminum hydroxide, Calcium acetate. The full list is on the Cholecalciferol page.
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