Drug interactions
Calcium chloride + Ergocalciferol
Severity: Moderate
Calcium chloride and Ergocalciferol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vitamin D increases intestinal calcium absorption, and calcium chloride adds to the calcium load. Together they can cause hypercalcemia, particularly in patients with renal impairment or at high doses.
What this interaction means in plain words
Calcium chloride and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic effect: vitamin D enhances calcium absorption and raises serum calcium.
What to do
Monitor serum calcium regularly, especially with prolonged or high-dose use, and reduce the dose of either agent if calcium rises.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ergocalciferol
- Aluminum hydroxide + Ergocalciferol Moderate
- Calcium acetate + Ergocalciferol Moderate
- Calcium carbonate + Ergocalciferol Moderate
- Calcium citrate + Ergocalciferol Moderate
- Calcium gluconate + Ergocalciferol Moderate
- Chlorothiazide + Ergocalciferol Moderate
Frequently asked questions
Can I take Calcium chloride with Ergocalciferol?
MediHelp rates the interaction as moderate. Calcium chloride and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vitamin D increases intestinal calcium absorption, and calcium chloride adds to the calcium load. Together they can cause hypercalcemia, particularly in patients with renal impairment or at high doses.
How serious is the interaction between Calcium chloride and Ergocalciferol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium regularly, especially with prolonged or high-dose use, and reduce the dose of either agent if calcium rises.
What other medicines interact with Ergocalciferol?
MediHelp also lists interactions of Ergocalciferol with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ergocalciferol page.
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