Drug interactions
Calcium carbonate + Ergocalciferol
Severity: Moderate
Calcium carbonate and Ergocalciferol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The combination is commonly used on purpose, but vitamin D increases calcium absorption and high intake can cause hypercalcemia. Risk is higher in renal impairment or with high doses.
What this interaction means in plain words
Calcium carbonate and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Ergocalciferol belongs to Musculoskeletal.
Why it happens
Vitamin D increases intestinal calcium absorption, producing additive effects on serum calcium.
What to do
Monitor serum calcium periodically, and adjust the doses of either agent if hypercalcemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ergocalciferol
- Aluminum hydroxide + Ergocalciferol Moderate
- Calcium acetate + Ergocalciferol Moderate
- Calcium chloride + Ergocalciferol Moderate
- Calcium citrate + Ergocalciferol Moderate
- Calcium gluconate + Ergocalciferol Moderate
- Chlorothiazide + Ergocalciferol Moderate
Other interactions of Calcium carbonate
Frequently asked questions
Can I take Calcium carbonate with Ergocalciferol?
MediHelp rates the interaction as moderate. Calcium carbonate and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The combination is commonly used on purpose, but vitamin D increases calcium absorption and high intake can cause hypercalcemia. Risk is higher in renal impairment or with high doses.
How serious is the interaction between Calcium carbonate and Ergocalciferol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium periodically, and adjust the doses of either agent if hypercalcemia occurs.
What other medicines interact with Ergocalciferol?
MediHelp also lists interactions of Ergocalciferol with, for example, Aluminum hydroxide, Calcium acetate, Calcium chloride. The full list is on the Ergocalciferol page.
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