Drug interactions
Calcium acetate + Ergocalciferol
Severity: Moderate
Calcium acetate and Ergocalciferol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vitamin D increases intestinal calcium absorption, and calcium acetate adds to the calcium load. Together they can cause hypercalcemia, particularly in patients with renal impairment or at high doses.
What this interaction means in plain words
Calcium acetate and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium acetate belongs to Genitourinary; Ergocalciferol belongs to Musculoskeletal.
Why it happens
Additive pharmacodynamic effect: vitamin D enhances intestinal calcium absorption from the administered calcium salt.
What to do
Monitor serum calcium and phosphate periodically and adjust the dose of either agent if hypercalcemia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ergocalciferol
- Aluminum hydroxide + Ergocalciferol Moderate
- Calcium carbonate + Ergocalciferol Moderate
- Calcium chloride + Ergocalciferol Moderate
- Calcium citrate + Ergocalciferol Moderate
- Calcium gluconate + Ergocalciferol Moderate
- Chlorothiazide + Ergocalciferol Moderate
Other interactions of Calcium acetate
Frequently asked questions
Can I take Calcium acetate with Ergocalciferol?
MediHelp rates the interaction as moderate. Calcium acetate and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vitamin D increases intestinal calcium absorption, and calcium acetate adds to the calcium load. Together they can cause hypercalcemia, particularly in patients with renal impairment or at high doses.
How serious is the interaction between Calcium acetate and Ergocalciferol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and phosphate periodically and adjust the dose of either agent if hypercalcemia develops.
What other medicines interact with Ergocalciferol?
MediHelp also lists interactions of Ergocalciferol with, for example, Aluminum hydroxide, Calcium carbonate, Calcium chloride. The full list is on the Ergocalciferol page.
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