Drug interactions
Calcium gluconate + Prednisone
Severity: Minor
Calcium gluconate and Prednisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids reduce intestinal calcium absorption and increase urinary calcium loss. Calcium requirements may be higher in patients on prolonged prednisone.
What this interaction means in plain words
Calcium gluconate and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium gluconate belongs to Gastrointestinal Tract; Prednisone belongs to Endocrine.
Why it happens
Glucocorticoids decrease gastrointestinal calcium absorption and increase renal calcium excretion.
What to do
Monitor serum calcium and adjust calcium dosing to response in patients on long-term prednisone.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Calcium gluconate
- Calcium gluconate + Ceftriaxone Contraindicated
- Calcium gluconate + Digoxin Major
- Alendronate + Calcium gluconate Moderate
- Amlodipine-atorvastatin + Calcium gluconate Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate Moderate
Frequently asked questions
Can I take Calcium gluconate with Prednisone?
MediHelp rates the interaction as minor. Calcium gluconate and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids reduce intestinal calcium absorption and increase urinary calcium loss. Calcium requirements may be higher in patients on prolonged prednisone.
How serious is the interaction between Calcium gluconate and Prednisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and adjust calcium dosing to response in patients on long-term prednisone.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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