Drug interactions
Candesartan + Insulin degludec-insulin aspart
Severity: Minor
Candesartan and Insulin degludec-insulin aspart: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity and in some patients enhance the glucose-lowering effect of insulin. Hypoglycemia is occasionally reported, mostly after starting the ARB.
What this interaction means in plain words
Candesartan and Insulin degludec-insulin aspart have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Candesartan belongs to Cardiovascular; Insulin degludec-insulin aspart belongs to Endocrine.
Why it happens
Angiotensin II blockade may improve peripheral insulin sensitivity, adding to insulin's effect.
What to do
Monitor blood glucose when starting or stopping candesartan and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-insulin aspart
- Chlorpropamide + Insulin degludec-insulin aspart Major
- Clozapine + Insulin degludec-insulin aspart Major
- Diazoxide + Insulin degludec-insulin aspart Major
- Ethanol + Insulin degludec-insulin aspart Major
- Insulin degludec-insulin aspart + Mecasermin Major
- Insulin degludec-insulin aspart + Pioglitazone Major
Other interactions of Candesartan
- Aliskiren + Candesartan Contraindicated
- Candesartan + Sparsentan Contraindicated
- Amifostine + Candesartan Major
- Amiloride + Candesartan Major
- Amlodipine-benazepril + Candesartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Candesartan Major
Frequently asked questions
Can I take Candesartan with Insulin degludec-insulin aspart?
MediHelp rates the interaction as minor. Candesartan and Insulin degludec-insulin aspart have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may improve insulin sensitivity and in some patients enhance the glucose-lowering effect of insulin. Hypoglycemia is occasionally reported, mostly after starting the ARB.
How serious is the interaction between Candesartan and Insulin degludec-insulin aspart?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping candesartan and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
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