Drug interactions
Capivasertib + Haloperidol
Severity: Minor
Capivasertib and Haloperidol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Capivasertib is metabolized by CYP3A4, and haloperidol is at most a weak inhibitor of this enzyme. A clinically meaningful rise in capivasertib exposure is uncertain.
What this interaction means in plain words
Capivasertib and Haloperidol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Capivasertib belongs to Oncology; Haloperidol belongs to Central Nervous System.
Why it happens
Possible weak CYP3A4 inhibition by haloperidol.
What to do
Monitor for capivasertib adverse effects such as hyperglycemia, diarrhea and rash, adjusting the dose if toxicity develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Other interactions of Capivasertib
Frequently asked questions
Can I take Capivasertib with Haloperidol?
MediHelp rates the interaction as minor. Capivasertib and Haloperidol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Capivasertib is metabolized by CYP3A4, and haloperidol is at most a weak inhibitor of this enzyme. A clinically meaningful rise in capivasertib exposure is uncertain.
How serious is the interaction between Capivasertib and Haloperidol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for capivasertib adverse effects such as hyperglycemia, diarrhea and rash, adjusting the dose if toxicity develops.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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