Drug interactions
Captopril-hydrochlorothiazide + Nabilone
Severity: Minor
Captopril-hydrochlorothiazide and Nabilone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nabilone can cause orthostatic hypotension and tachycardia, which may add to the blood pressure lowering of captopril and hydrochlorothiazide. Dizziness and falls are the main concerns, particularly in older adults.
What this interaction means in plain words
Captopril-hydrochlorothiazide and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Captopril-hydrochlorothiazide belongs to Cardiovascular; Nabilone belongs to Gastrointestinal Tract.
Why it happens
Additive hypotensive effects from cannabinoid-induced vasodilation and the antihypertensive combination.
What to do
Monitor blood pressure and warn patients about dizziness on standing, especially after dose changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Other interactions of Nabilone
Frequently asked questions
Can I take Captopril-hydrochlorothiazide with Nabilone?
MediHelp rates the interaction as minor. Captopril-hydrochlorothiazide and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nabilone can cause orthostatic hypotension and tachycardia, which may add to the blood pressure lowering of captopril and hydrochlorothiazide. Dizziness and falls are the main concerns, particularly in older adults.
How serious is the interaction between Captopril-hydrochlorothiazide and Nabilone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and warn patients about dizziness on standing, especially after dose changes.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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