Drug interactions
Carbinoxamine + Desflurane
Severity: Minor
Carbinoxamine and Desflurane: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbinoxamine is a sedating first-generation antihistamine with anticholinergic activity. With desflurane it may increase drowsiness and delay recovery. The effect is typically modest.
What this interaction means in plain words
Carbinoxamine and Desflurane have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carbinoxamine belongs to Respiratory; Desflurane belongs to Central Nervous System.
Why it happens
Additive CNS depression through H1 antagonism and general anesthetic action.
What to do
Titrate desflurane to effect and monitor postoperative sedation. Advise patients to avoid other sedatives immediately after surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Desflurane
Other interactions of Carbinoxamine
- Alprazolam + Carbinoxamine Moderate
- Amisulpride + Carbinoxamine Moderate
- Amitriptyline + Carbinoxamine Moderate
- Amobarbital + Carbinoxamine Moderate
- Asenapine + Carbinoxamine Moderate
- Azelastine-fluticasone + Carbinoxamine Moderate
Frequently asked questions
Can I take Carbinoxamine with Desflurane?
MediHelp rates the interaction as minor. Carbinoxamine and Desflurane have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Carbinoxamine is a sedating first-generation antihistamine with anticholinergic activity. With desflurane it may increase drowsiness and delay recovery. The effect is typically modest.
How serious is the interaction between Carbinoxamine and Desflurane?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate desflurane to effect and monitor postoperative sedation. Advise patients to avoid other sedatives immediately after surgery.
What other medicines interact with Desflurane?
MediHelp also lists interactions of Desflurane with, for example, Amisulpride, Anagrelide, Arsenic trioxide. The full list is on the Desflurane page.
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