Drug interactions
Carbinoxamine + Lurasidone
Severity: Minor
Carbinoxamine and Lurasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbinoxamine is a sedating first-generation antihistamine with anticholinergic effects. Combined with lurasidone it may increase drowsiness, impaired psychomotor performance and anticholinergic effects.
What this interaction means in plain words
Carbinoxamine and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carbinoxamine belongs to Respiratory; Lurasidone belongs to Central Nervous System.
Why it happens
Additive CNS depression and anticholinergic effects from antihistamine and antipsychotic properties.
What to do
Counsel patients about drowsiness and avoidance of alcohol and driving if sedated. Consider a non-sedating antihistamine if the combination is poorly tolerated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Other interactions of Carbinoxamine
- Alprazolam + Carbinoxamine Moderate
- Amisulpride + Carbinoxamine Moderate
- Amitriptyline + Carbinoxamine Moderate
- Amobarbital + Carbinoxamine Moderate
- Asenapine + Carbinoxamine Moderate
- Azelastine-fluticasone + Carbinoxamine Moderate
Frequently asked questions
Can I take Carbinoxamine with Lurasidone?
MediHelp rates the interaction as minor. Carbinoxamine and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Carbinoxamine is a sedating first-generation antihistamine with anticholinergic effects. Combined with lurasidone it may increase drowsiness, impaired psychomotor performance and anticholinergic effects.
How serious is the interaction between Carbinoxamine and Lurasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about drowsiness and avoidance of alcohol and driving if sedated. Consider a non-sedating antihistamine if the combination is poorly tolerated.
What other medicines interact with Lurasidone?
MediHelp also lists interactions of Lurasidone with, for example, Apalutamide, Atazanavir, Carbamazepine. The full list is on the Lurasidone page.
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