Drug interactions
Cariprazine + Etravirine
Severity: Moderate
Cariprazine and Etravirine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etravirine induces CYP3A4 and may lower concentrations of cariprazine and its active metabolites. The net effect is unclear but reduced efficacy is possible.
What this interaction means in plain words
Cariprazine and Etravirine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cariprazine belongs to Central Nervous System; Etravirine belongs to Anti Virals.
Why it happens
Etravirine is a modest CYP3A4 inducer that may increase cariprazine clearance.
What to do
Monitor for loss of antipsychotic effect and adjust the cariprazine dose according to clinical response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cariprazine
Other interactions of Etravirine
- Efavirenz + Etravirine Contraindicated
- Etravirine + Isavuconazole Contraindicated
- Amobarbital + Etravirine Major
- Apalutamide + Etravirine Major
- Carbamazepine + Etravirine Major
- Cobicistat + Etravirine Major
Frequently asked questions
Can I take Cariprazine with Etravirine?
MediHelp rates the interaction as moderate. Cariprazine and Etravirine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Etravirine induces CYP3A4 and may lower concentrations of cariprazine and its active metabolites. The net effect is unclear but reduced efficacy is possible.
How serious is the interaction between Cariprazine and Etravirine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for loss of antipsychotic effect and adjust the cariprazine dose according to clinical response.
What other medicines interact with Cariprazine?
MediHelp also lists interactions of Cariprazine with, for example, Alfentanil, Amisulpride, Amobarbital. The full list is on the Cariprazine page.
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