Drug interactions
Cariprazine + Lasmiditan
Severity: Moderate
Cariprazine and Lasmiditan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan commonly causes dizziness and sedation, and cariprazine can cause somnolence. Used together, they may increase drowsiness and cognitive or psychomotor impairment.
What this interaction means in plain words
Cariprazine and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cariprazine belongs to Central Nervous System; Lasmiditan belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects (pharmacodynamic).
What to do
Advise the patient not to drive or operate machinery for at least 8 hours after each lasmiditan dose. Monitor for excessive sedation.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cariprazine
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Cariprazine with Lasmiditan?
MediHelp rates the interaction as moderate. Cariprazine and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan commonly causes dizziness and sedation, and cariprazine can cause somnolence. Used together, they may increase drowsiness and cognitive or psychomotor impairment.
How serious is the interaction between Cariprazine and Lasmiditan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise the patient not to drive or operate machinery for at least 8 hours after each lasmiditan dose. Monitor for excessive sedation.
What other medicines interact with Cariprazine?
MediHelp also lists interactions of Cariprazine with, for example, Alfentanil, Amisulpride, Amobarbital. The full list is on the Cariprazine page.
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