Drug interactions
Cefazolin + Dalteparin
Severity: Minor
Cefazolin and Dalteparin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefazolin has little effect on coagulation, so a meaningful interaction with dalteparin is not well established. Any added bleeding risk is theoretical.
What this interaction means in plain words
Cefazolin and Dalteparin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefazolin belongs to Anti Bacterial; Dalteparin belongs to Cardiovascular.
Why it happens
No established mechanism; a theoretical additive effect on hemostasis.
What to do
No specific action beyond routine bleeding surveillance during dalteparin therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefazolin
- Amikacin + Cefazolin Moderate
- Bcg vaccine live + Cefazolin Moderate
- Cefazolin + Cholera vaccine Moderate
- Cefazolin + Dexamethasone-tobramycin Moderate
- Cefazolin + Gentamicin Moderate
- Cefazolin + Kanamycin Moderate
Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Frequently asked questions
Can I take Cefazolin with Dalteparin?
MediHelp rates the interaction as minor. Cefazolin and Dalteparin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefazolin has little effect on coagulation, so a meaningful interaction with dalteparin is not well established. Any added bleeding risk is theoretical.
How serious is the interaction between Cefazolin and Dalteparin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action beyond routine bleeding surveillance during dalteparin therapy.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefazolin page.
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