Drug interactions
Cefdinir + Cimetidine
Severity: Minor
Cefdinir and Cimetidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Acid-suppressing drugs may modestly reduce oral cefdinir absorption. This might lower antibiotic effectiveness in some infections.
What this interaction means in plain words
Cefdinir and Cimetidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefdinir belongs to Anti Bacterial; Cimetidine belongs to Gastrointestinal Tract.
Why it happens
Higher gastric pH reduces cefdinir absorption.
What to do
Usually no change is needed. Consider a different antibiotic if absorption is a concern in serious infection.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cimetidine
- Cimetidine + Dofetilide Contraindicated
- Cimetidine + Fezolinetant Contraindicated
- Alfentanil + Cimetidine Major
- Atazanavir + Cimetidine Major
- Carmustine + Cimetidine Major
- Cimetidine + Citalopram Major
Other interactions of Cefdinir
- Aluminum hydroxide + Cefdinir Moderate
- Cefdinir + Cholera vaccine Moderate
- Cefdinir + Famotidine Moderate
- Cefdinir + Gentamicin Moderate
- Cefdinir + Microbiota Moderate
- Cefdinir + Nizatidine Moderate
Frequently asked questions
Can I take Cefdinir with Cimetidine?
MediHelp rates the interaction as minor. Cefdinir and Cimetidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Acid-suppressing drugs may modestly reduce oral cefdinir absorption. This might lower antibiotic effectiveness in some infections.
How serious is the interaction between Cefdinir and Cimetidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Usually no change is needed. Consider a different antibiotic if absorption is a concern in serious infection.
What other medicines interact with Cimetidine?
MediHelp also lists interactions of Cimetidine with, for example, Dofetilide, Fezolinetant, Alfentanil. The full list is on the Cimetidine page.
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