Drug interactions
Cefpirome + Ganciclovir
Severity: Minor
Cefpirome and Ganciclovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefpirome is renally eliminated and might compete with ganciclovir for tubular secretion, theoretically increasing ganciclovir concentrations. No meaningful clinical effect has been established.
What this interaction means in plain words
Cefpirome and Ganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefpirome belongs to Anti Bacterial; Ganciclovir belongs to Anti Virals.
Why it happens
Theoretical competition for renal tubular anionic secretion.
What to do
No routine change is needed; monitor renal function and blood counts in patients with reduced kidney function. Dose both drugs according to creatinine clearance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ganciclovir
Other interactions of Cefpirome
- Amikacin + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
Frequently asked questions
Can I take Cefpirome with Ganciclovir?
MediHelp rates the interaction as minor. Cefpirome and Ganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefpirome is renally eliminated and might compete with ganciclovir for tubular secretion, theoretically increasing ganciclovir concentrations. No meaningful clinical effect has been established.
How serious is the interaction between Cefpirome and Ganciclovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor renal function and blood counts in patients with reduced kidney function. Dose both drugs according to creatinine clearance.
What other medicines interact with Ganciclovir?
MediHelp also lists interactions of Ganciclovir with, for example, Bacitracin, Cilastatin-imipenem, Didanosine. The full list is on the Ganciclovir page.
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