Drug interactions
Cefpirome + Ketorolac
Severity: Minor
Cefpirome and Ketorolac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are renally secreted acidic compounds, and competition might slightly raise ketorolac exposure. Clinical relevance is likely small in patients with normal renal function.
What this interaction means in plain words
Cefpirome and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefpirome belongs to Anti Bacterial; Ketorolac belongs to Musculoskeletal.
Why it happens
Competition for renal tubular anion secretion may reduce clearance of either drug.
What to do
No specific adjustment is needed; monitor renal function and for NSAID adverse effects in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Other interactions of Cefpirome
- Amikacin + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
Frequently asked questions
Can I take Cefpirome with Ketorolac?
MediHelp rates the interaction as minor. Cefpirome and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both are renally secreted acidic compounds, and competition might slightly raise ketorolac exposure. Clinical relevance is likely small in patients with normal renal function.
How serious is the interaction between Cefpirome and Ketorolac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific adjustment is needed; monitor renal function and for NSAID adverse effects in patients with renal impairment.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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