Drug interactions
Cefprozil + Furosemide
Severity: Minor
Cefprozil and Furosemide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Furosemide can reduce the renal tubular secretion of cefprozil, which may modestly raise cefprozil levels. Loop diuretics may also add to renal stress with some cephalosporins. The effect is usually small at standard doses.
What this interaction means in plain words
Cefprozil and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefprozil belongs to Anti Bacterial; Furosemide belongs to Cardiovascular.
Why it happens
Competition for renal tubular anionic transport reduces cefprozil clearance.
What to do
No dose change is usually needed in patients with normal kidney function. Monitor renal function in patients with renal impairment or volume depletion.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefprozil
- Amikacin + Cefprozil Moderate
- Bcg vaccine live + Cefprozil Moderate
- Cefprozil + Cholera vaccine Moderate
- Cefprozil + Gentamicin Moderate
- Cefprozil + Microbiota Moderate
- Cefprozil + Plazomicin Moderate
Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Cefprozil with Furosemide?
MediHelp rates the interaction as minor. Cefprozil and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Furosemide can reduce the renal tubular secretion of cefprozil, which may modestly raise cefprozil levels. Loop diuretics may also add to renal stress with some cephalosporins. The effect is usually small at standard doses.
How serious is the interaction between Cefprozil and Furosemide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed in patients with normal kidney function. Monitor renal function in patients with renal impairment or volume depletion.
What other medicines interact with Cefprozil?
MediHelp also lists interactions of Cefprozil with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefprozil page.
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