Drug interactions
Celecoxib + Etravirine
Severity: Minor
Celecoxib and Etravirine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etravirine inhibits CYP2C9 and CYP2C19 and may raise exposure to celecoxib. The effect is probably modest, but celecoxib adverse effects could increase.
What this interaction means in plain words
Celecoxib and Etravirine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Celecoxib belongs to Musculoskeletal; Etravirine belongs to Anti Virals.
Why it happens
Etravirine inhibition of CYP2C9 reduces celecoxib clearance.
What to do
Monitor for celecoxib adverse effects, including renal function and blood pressure. Reduce the celecoxib dose if toxicity appears.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Other interactions of Etravirine
- Efavirenz + Etravirine Contraindicated
- Etravirine + Isavuconazole Contraindicated
- Amobarbital + Etravirine Major
- Apalutamide + Etravirine Major
- Carbamazepine + Etravirine Major
- Cobicistat + Etravirine Major
Frequently asked questions
Can I take Celecoxib with Etravirine?
MediHelp rates the interaction as minor. Celecoxib and Etravirine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etravirine inhibits CYP2C9 and CYP2C19 and may raise exposure to celecoxib. The effect is probably modest, but celecoxib adverse effects could increase.
How serious is the interaction between Celecoxib and Etravirine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for celecoxib adverse effects, including renal function and blood pressure. Reduce the celecoxib dose if toxicity appears.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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