Drug interactions
Cenobamate + Fenofibric acid
Severity: Minor
Cenobamate and Fenofibric acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cenobamate induces CYP3A4, but fenofibric acid is cleared mainly by glucuronidation and renal elimination. A meaningful change in exposure is not expected.
What this interaction means in plain words
Cenobamate and Fenofibric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cenobamate belongs to Central Nervous System; Fenofibric acid belongs to Cardiovascular.
Why it happens
Cenobamate induces CYP3A4, a negligible pathway for fenofibric acid, so any effect is predicted only.
What to do
No empiric dose change is needed. Check the lipid profile if cenobamate is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenofibric acid
- Atorvastatin + Fenofibric acid Moderate
- Chlorpropamide + Fenofibric acid Moderate
- Cholestyramine + Fenofibric acid Moderate
- Cholic acid + Fenofibric acid Moderate
- Colchicine + Fenofibric acid Moderate
- Colestipol + Fenofibric acid Moderate
Other interactions of Cenobamate
Frequently asked questions
Can I take Cenobamate with Fenofibric acid?
MediHelp rates the interaction as minor. Cenobamate and Fenofibric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cenobamate induces CYP3A4, but fenofibric acid is cleared mainly by glucuronidation and renal elimination. A meaningful change in exposure is not expected.
How serious is the interaction between Cenobamate and Fenofibric acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empiric dose change is needed. Check the lipid profile if cenobamate is started or stopped.
What other medicines interact with Fenofibric acid?
MediHelp also lists interactions of Fenofibric acid with, for example, Atorvastatin, Chlorpropamide, Cholestyramine. The full list is on the Fenofibric acid page.
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