Drug interactions
Colestipol + Fenofibric acid
Severity: Moderate
Colestipol and Fenofibric acid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bile acid sequestrants bind fibrates in the gut and can reduce their absorption. This may blunt the lipid-lowering effect of fenofibric acid if taken together.
What this interaction means in plain words
Colestipol and Fenofibric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colestipol belongs to Cardiovascular; Fenofibric acid belongs to Cardiovascular.
Why it happens
Colestipol binds fenofibric acid in the gastrointestinal tract, reducing its absorption.
What to do
Take fenofibric acid at least 1 hour before or 4 to 6 hours after colestipol. Monitor lipid response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fenofibric acid
- Atorvastatin + Fenofibric acid Moderate
- Chlorpropamide + Fenofibric acid Moderate
- Cholestyramine + Fenofibric acid Moderate
- Cholic acid + Fenofibric acid Moderate
- Colchicine + Fenofibric acid Moderate
- Cyclosporine + Fenofibric acid Moderate
Other interactions of Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderate
- Atenolol-chlorthalidone + Colestipol Moderate
- Azilsartan-chlorthalidone + Colestipol Moderate
- Candesartan-hydrochlorothiazide + Colestipol Moderate
- Captopril-hydrochlorothiazide + Colestipol Moderate
Frequently asked questions
Can I take Colestipol with Fenofibric acid?
MediHelp rates the interaction as moderate. Colestipol and Fenofibric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bile acid sequestrants bind fibrates in the gut and can reduce their absorption. This may blunt the lipid-lowering effect of fenofibric acid if taken together.
How serious is the interaction between Colestipol and Fenofibric acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take fenofibric acid at least 1 hour before or 4 to 6 hours after colestipol. Monitor lipid response.
What other medicines interact with Fenofibric acid?
MediHelp also lists interactions of Fenofibric acid with, for example, Atorvastatin, Chlorpropamide, Cholestyramine. The full list is on the Fenofibric acid page.
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