Drug interactions
Chlordiazepoxide-clidinium + Etravirine
Severity: Minor
Chlordiazepoxide-clidinium and Etravirine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etravirine may lower chlordiazepoxide exposure, potentially reducing its anxiolytic or withdrawal-suppressing effect. The clinical impact is usually modest.
What this interaction means in plain words
Chlordiazepoxide-clidinium and Etravirine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chlordiazepoxide-clidinium belongs to Gastrointestinal Tract; Etravirine belongs to Anti Virals.
Why it happens
Etravirine is a weak to moderate inducer of CYP3A4, which increases chlordiazepoxide metabolism.
What to do
Monitor for reduced clinical response and increase the chlordiazepoxide dose only if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chlordiazepoxide-clidinium
- Alfentanil + Chlordiazepoxide-clidinium Major
- Alprazolam + Chlordiazepoxide-clidinium Major
- Amobarbital + Chlordiazepoxide-clidinium Major
- Belladonna and opium + Chlordiazepoxide-clidinium Major
- Benzhydrocodone / acetaminophen + Chlordiazepoxide-clidinium Major
- Brexanolone + Chlordiazepoxide-clidinium Major
Other interactions of Etravirine
- Efavirenz + Etravirine Contraindicated
- Etravirine + Isavuconazole Contraindicated
- Amobarbital + Etravirine Major
- Apalutamide + Etravirine Major
- Carbamazepine + Etravirine Major
- Cobicistat + Etravirine Major
Frequently asked questions
Can I take Chlordiazepoxide-clidinium with Etravirine?
MediHelp rates the interaction as minor. Chlordiazepoxide-clidinium and Etravirine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etravirine may lower chlordiazepoxide exposure, potentially reducing its anxiolytic or withdrawal-suppressing effect. The clinical impact is usually modest.
How serious is the interaction between Chlordiazepoxide-clidinium and Etravirine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced clinical response and increase the chlordiazepoxide dose only if needed.
What other medicines interact with Chlordiazepoxide-clidinium?
MediHelp also lists interactions of Chlordiazepoxide-clidinium with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide-clidinium page.
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