Drug interactions
Chloroquine + Galantamine
Severity: Minor
Chloroquine and Galantamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine may raise galantamine levels by inhibiting CYP2D6. Higher exposure may increase cholinergic effects such as nausea, vomiting and bradycardia.
What this interaction means in plain words
Chloroquine and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chloroquine belongs to Anti Parasitic; Galantamine belongs to Central Nervous System.
Why it happens
CYP2D6 inhibition by chloroquine reduces galantamine metabolism.
What to do
Monitor heart rate and gastrointestinal tolerance and reduce the galantamine dose if adverse effects arise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Other interactions of Galantamine
- Galantamine + Memantine-donepezil Major
- Galantamine + Physostigmine Major
- Galantamine + Ponesimod Major
- Galantamine + Rivastigmine Major
- Amifampridine + Galantamine Moderate
- Amiodarone + Galantamine Moderate
Frequently asked questions
Can I take Chloroquine with Galantamine?
MediHelp rates the interaction as minor. Chloroquine and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chloroquine may raise galantamine levels by inhibiting CYP2D6. Higher exposure may increase cholinergic effects such as nausea, vomiting and bradycardia.
How serious is the interaction between Chloroquine and Galantamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and gastrointestinal tolerance and reduce the galantamine dose if adverse effects arise.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
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