Drug interactions
Chloroquine + Salbutamol
Severity: Moderate
Chloroquine and Salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine prolongs the QT interval, and salbutamol can add to arrhythmia risk through tachycardia and hypokalemia. The combination may be of concern in patients with other risk factors.
What this interaction means in plain words
Chloroquine and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chloroquine belongs to Anti Parasitic; Salbutamol belongs to Respiratory.
Why it happens
Additive QT prolongation with beta-2 agonist-induced hypokalemia.
What to do
Check potassium and consider an ECG in patients with cardiac disease or other QT-prolonging drugs; correct electrolyte abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Salbutamol?
MediHelp rates the interaction as moderate. Chloroquine and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine prolongs the QT interval, and salbutamol can add to arrhythmia risk through tachycardia and hypokalemia. The combination may be of concern in patients with other risk factors.
How serious is the interaction between Chloroquine and Salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and consider an ECG in patients with cardiac disease or other QT-prolonging drugs; correct electrolyte abnormalities.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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