Drug interactions
Chloroquine + Triptorelin
Severity: Moderate
Chloroquine and Triptorelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgen deprivation therapy with triptorelin can prolong the QT interval, and chloroquine adds to this effect. The combination increases the risk of torsades de pointes.
What this interaction means in plain words
Chloroquine and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chloroquine belongs to Anti Parasitic; Triptorelin belongs to Endocrine.
Why it happens
Additive QT prolongation.
What to do
Obtain a baseline ECG and correct electrolyte abnormalities. Monitor ECG during co-therapy in patients with cardiac risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Other interactions of Triptorelin
Frequently asked questions
Can I take Chloroquine with Triptorelin?
MediHelp rates the interaction as moderate. Chloroquine and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgen deprivation therapy with triptorelin can prolong the QT interval, and chloroquine adds to this effect. The combination increases the risk of torsades de pointes.
How serious is the interaction between Chloroquine and Triptorelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct electrolyte abnormalities. Monitor ECG during co-therapy in patients with cardiac risk factors.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
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