Drug interactions
Chlorpromazine + Indacaterol inhaled
Severity: Moderate
Chlorpromazine and Indacaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chlorpromazine prolongs the QT interval and indacaterol, a beta-2 agonist, can affect cardiac repolarization and lower potassium. Together they may increase the risk of ventricular arrhythmias, particularly in patients with heart disease.
What this interaction means in plain words
Chlorpromazine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QTc prolongation and beta-agonist-related hypokalemia and tachycardia.
What to do
Monitor ECG and serum potassium in patients with cardiac risk factors. Consider an alternative bronchodilator or antipsychotic if QTc prolongation develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chlorpromazine
- Chlorpromazine + Dofetilide Contraindicated
- Chlorpromazine + Dronedarone Contraindicated
- Chlorpromazine + Droperidol Contraindicated
- Chlorpromazine + Ibutilide Contraindicated
- Chlorpromazine + Metrizamide Contraindicated
- Chlorpromazine + Panobinostat Contraindicated
Frequently asked questions
Can I take Chlorpromazine with Indacaterol inhaled?
MediHelp rates the interaction as moderate. Chlorpromazine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chlorpromazine prolongs the QT interval and indacaterol, a beta-2 agonist, can affect cardiac repolarization and lower potassium. Together they may increase the risk of ventricular arrhythmias, particularly in patients with heart disease.
How serious is the interaction between Chlorpromazine and Indacaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with cardiac risk factors. Consider an alternative bronchodilator or antipsychotic if QTc prolongation develops.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Droperidol. The full list is on the Chlorpromazine page.
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