Drug interactions
Chlorpromazine + Levosalbutamol
Severity: Minor
Chlorpromazine and Levosalbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chlorpromazine can prolong the QT interval and cause hypotension, while levosalbutamol can cause tachycardia and lower potassium. Together these may increase arrhythmia risk, mainly with high doses or predisposing conditions.
What this interaction means in plain words
Chlorpromazine and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chlorpromazine belongs to Central Nervous System; Levosalbutamol belongs to Respiratory.
Why it happens
Additive effects on cardiac repolarization and heart rate; beta-2 agonist induced hypokalemia may potentiate QT effects.
What to do
Monitor ECG and potassium in patients with cardiac risk factors or on high-dose beta-agonist therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levosalbutamol
Other interactions of Chlorpromazine
- Chlorpromazine + Dofetilide Contraindicated
- Chlorpromazine + Dronedarone Contraindicated
- Chlorpromazine + Droperidol Contraindicated
- Chlorpromazine + Ibutilide Contraindicated
- Chlorpromazine + Metrizamide Contraindicated
- Chlorpromazine + Panobinostat Contraindicated
Frequently asked questions
Can I take Chlorpromazine with Levosalbutamol?
MediHelp rates the interaction as minor. Chlorpromazine and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chlorpromazine can prolong the QT interval and cause hypotension, while levosalbutamol can cause tachycardia and lower potassium. Together these may increase arrhythmia risk, mainly with high doses or predisposing conditions.
How serious is the interaction between Chlorpromazine and Levosalbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and potassium in patients with cardiac risk factors or on high-dose beta-agonist therapy.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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